Aortic Stenosis and Gastrointestinal Bleeding

Heyde syndrome: gastrointestinal bleeding and aortic stenosis.

Gastrointestinal Bleeding due to Angiodysplasia in a Patient with Severe Aortic Stenosis: Heyde’s Syndrome

There is a frequent association between aortic valve stenosis and gastrointestinal bleeding, also known as Heyde’s syndrome. The pathophysiologic basis for this syndrome seems to be an acquired von Willebrand factor deficiency, leading to bleeding of angiodysplastic arteriovenous malformations. Treatment options include the location and cauterization of bleeding points, which is associated to h...

Clinical implication of gastrointestinal bleeding in degenerative aortic stenosis: an update.

Gastrointestinal (GI) bleeding due to colonic angiodysplasias can be associated with calcifying aortic stenosis (AS). GI angiodysplasias and AS are defined as chronic degenerative disorders, and the prevalence of both diseases increases with age. Moreover, degenerative AS is associated with increased destruction of high molecular weight multimers of von Willebrand factor which can promote bleed...

Severe Calcific Aortic Valve Stenosis and Bleeding: Heyde's Syndrome

In 1958 Dr. Edward C. Heyde, an internist living and working in Vancouver, WA, first reported in a letter to the New England Journal of Medicine, 10 cases of calcific aortic stenosis and grastrointestinal bleeding. The association between severe calcific aortic stenosis and iron deficency anemia due gastrointestinal bleeding, from colonic angiodysplasia was described as Heyde syndrome. A letter...

Gastrointestinal bleeding after aortic surgery: a case report

INTRODUCTION An aortoenteric fistula is a communication between the aorta and an adjacent loop of the bowel. Here we report a case with this rare complication with typical herald bleeding. CASE REPORT A 66-year-old man underwent elective repair of a large supra-renal abdominal aortic aneurysm and returned 6 months later to our clinic after experiencing a melena with hematochezia. The source o...